20 09, 2021

Uttar Pradesh, India Announces State Is COVID-19 Free Proving the Effectiveness of “Deworming Drug” IVERMECTIN

September 20, 2021|International, Ivermectin|

COVID cases are plummeting in India thanks to new rules that promote Ivermectin and hydroxychloroquine to its massive population. The 33 districts in Uttar Pradesh, India have now become free from COVID-19 government informed on Friday. The recovery rate has increased up to 98.7% proving the effectiveness of IVERMECTIN as part of […]

14 09, 2021

Ivermectin, a potential anticancer drug derived from an antiparasitic drug

September 14, 2021|Ivermectin, Research|

Abstract

Ivermectin has powerful antitumor effects, including the inhibition of proliferation, metastasis, and angiogenic activity, in a variety of cancer cells. This may be related to the regulation of multiple signaling pathways by ivermectin through PAK1 kinase. On the other hand, ivermectin promotes programmed cancer cell death, including apoptosis, […]

10 09, 2021

Ivermectin: Australian regulator bans drug as Covid treatment after sharp rise in prescriptions

September 10, 2021|Australia, Ivermectin|

Australia’s drug regulator has banned medical practitioners from prescribing the anti-parasitic drug ivermectin for “off-label” uses, such as for treating Covid-19.

The move comes after prescriptions for the drug increased between three and four times in Australia in recent months.

The Therapeutic Goods Administration announced the ban on Friday afternoon, acting […]

25 08, 2021

Review of the Emerging Evidence Demonstrating the Efficacy of Ivermectin in the Prophylaxis and Treatment of COVID-19

August 25, 2021|International, Ivermectin, Research|

Conclusions:

Meta-analyses based on 18 randomized controlled treatment trials of ivermectin in COVID-19 have found large, statistically significant reductions in mortality, time to clinical recovery, and time to viral clearance. Furthermore, results from numerous controlled prophylaxis trials report significantly reduced risks of contracting COVID-19 with the regular use of ivermectin. Finally, the […]

20 08, 2021

Ivermectin inhibits LPS-induced production of inflammatory cytokines and improves LPS-induced survival in mice

August 20, 2021|Ivermectin, Research|

Abstract

Objective and design: To investigate whether ivermectin, a semi-synthetic derivative of a family of macrocyclic lactones could inhibit lipopolysaccharide (LPS)-induced inflammation in vivo and in vitro.

Materials and methods: C57BL/6 mice were administered ivermectin (or saline) orally and challenged intraperitoneally with LPS at a […]

20 08, 2021

Ivermectin for Prevention and Treatment of COVID-19 Infection: A Systematic Review, Meta-analysis, and Trial Sequential Analysis to Inform Clinical Guidelines

August 20, 2021|Ivermectin, Research|

Abstract

Background:

Repurposed medicines may have a role against the SARS-CoV-2 virus. The antiparasitic ivermectin, with antiviral and anti-inflammatory properties, has now been tested in numerous clinical trials.

Areas of uncertainty:

We assessed the efficacy of ivermectin treatment in reducing mortality, in secondary outcomes, and in chemoprophylaxis, among people […]

22 06, 2021

The mechanisms of action of Ivermectin against SARS-CoV-2: An evidence-based clinical review article

June 22, 2021|International, Ivermectin, Research|

Considering the urgency of the ongoing COVID-19 pandemic, detection of various new mutant strains and future potential re-emergence of novel coronaviruses, repurposing of approved drugs such as Ivermectin could be worthy of attention. This evidence-based review article aims to discuss the mechanism of action of ivermectin against SARS-CoV-2 and summarizing the available literature over the […]